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ea0016p369 | Growth factors | ECE2008

New occurrence of diabetes mellitus in patients with adult onset GH deficiency (GHD) on GH therapy is dependent on the presence of metabolic syndrome at baseline: data from the Hypopituitary Control and Complication Study (HypoCCS)

Attanasio Andrea , Mo Daojun , Chanson Philippe , Ho Ken , Woodmansee Whitney , Kleinberg David , Erfurth Eva Marie

Patients with adult onset GHD (AO-GHD) manifest features of the metabolic syndrome (MetS) (abdominal obesity, dyslipidemia and insulin resistance), a condition associated with increased risk of diabetes mellitus (DM).We assessed metabolic status before and after 2 years of GH treatment and the occurrence of de novo DM in 712 patients with AO-GHD from HypoCCS drawn from the US (32.2%) and Europe (67.8%). Patients were divided into four BMI categori...

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Endocrine Abstracts

New occurrence of diabetes mellitus in patients with adult onset GH deficiency (GHD) on GH therapy is dependent on the presence of metabolic syndrome at baseline: data from the Hypopituitary Control and Complication Study (HypoCCS)

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